Clinical evidence indicates that inflammatory bowel disease (IBD) and ankylosing spondylitis (AS) often co-occur, but their genetic mechanisms remain unclear. Our objective is to explore the genetic relationship between IBD and AS./r/nUsing large-scale summary statistics from genome-wide […]

To compare the risk of incident uveitis among patients with axial spondyloarthritis initiating treatment with Janus kinase inhibitors (JAKi) versus tumor necrosis factor inhibitors (TNFi)./r/nWe conducted an emulated target trial using real-world electronic health records from the TriNetX US […]

Spinal cord stimulation (SCS) is considered an efficient and safe method of treating intractable chronic pain from various origins such as persistent spinal pain syndrome (PSPS) or complex regional pain syndrome (CRPS). The complications related to SCS therapy are usually classified as mechanical […]

BACKGROUND Paravertebral extraskeletal Ewing sarcoma located in the extradural region is uncommon. Muscle denervation can be caused by nerve injury, destruction of the neuromuscular junctions, and aging-related loss of motor neurons. Psoas denervation caused by spinal extraskeletal Ewing sarcoma is […]

The superoxide dismutase type 1 (SOD1) gene has been implicated in both sporadic and familial forms of amyotrophic lateral sclerosis (ALS). We report four ALS cases carrying pathogenic or likely pathogenic SOD1 variants, characterized by albuminocytologic dissociation and nerve root […]

The ASAS consensus defines 'early axial spondyloarthritis (axSpA)' as symptom duration ≤2 years, a definition derived from expert opinion due to limited evidence. We performed a meta-analysis of randomized placebo-controlled trials (RCTs) of biologic and targeted synthetic DMARDs […]

Lumbar disc herniation (LDH) is one of the most common causes of lower back pain, radiculopathy, and functional impairment. Intra-articular (IA) steroid injections, including transforaminal (TFESI), interlaminar (IESI), and caudal (CESI) epidural steroid injections, are commonly administered to […]

Less than 1% of head and neck tumors are in the parapharyngeal space (PPS). With complex anatomy, conventional surgery is challenging. Endoscopy-assisted transoral approach (EATA) minimizes trauma and scarring; however, criticism regarding infeasibility with large tumors led to the introduction of […]

A 10-year-old girl presented with a 16-month history of persistent head tilt, restricted neck motion, and neck pain. Imaging demonstrated chronic atlantoaxial rotatory subluxation (AARS) with underlying congenital C1 arch diastasis. Preoperative halo-gravity traction (HGT) was performed over 2.5 […]

Accurate diagnosis of sacral insufficiency fractures in oncology patients may be challenging. We describe 18 F-PSMA-1007 PET/CT findings of sacral insufficiency fracture in a patient with a history of prostate cancer and pelvic radiotherapy. The insufficiency fracture in the left sacral ala showed […]

Neuroendocrine tumors (NETs) are a heterogeneous group of tumors, which are usually indolent with metastatic disease at the initial presentation in most clinical situations. Intramedullary spinal cord metastasis (ICSM) is usually rare in the case of neuroendocrine tumors. Peptide receptor […]

Sacroiliac joint dysfunction (SIJD) accounts for 15-25% of chronic low back pain and often follows lumbar fusion. When conservative therapies fail, minimally invasive (MIS) SIJ fusion (SIJF) is indicated. The robot-assisted technique is feasible and safe, enhancing accuracy and reducing radiation […]

Complex and Revision Surgery: ASC and Beyond - Steven Girdler, MD & Brandon Hirsch, MD

MIS Lateral Lumbar Corpectomy - Kevin Swong, M.D.

The study was carried out to inform Medicare acupuncture coverage decisions addressing the gap in evidence on acupuncture effectiveness, specifically for older adults with chronic low back pain (CLBP)./r/nTo determine the effectiveness of standard acupuncture (SA) or SA plus maintenance (enhanced […]

A 19-year-old man presented with a progressive kyphoscoliosis deformity, pelvic obliquity, neck flexion, and bilateral lower limb contractures. Evaluation showed previously undiagnosed spinal osteoid osteoma. The patient underwent surgical resection with instrumentation of L3-L4. At the 2-year […]

Cage migration (CR) after lumbar interbody fusion may result in intractable complications to patients. This meta-analysis was aimed to figure out risk factors of cage migration after posterior approaches for lumbar interbody fusion./r/nLiterature was searched in the PubMed, Embase, Web of Science […]

Three-column osteotomy (3CO) offers substantial spinal deformity correction. Thoracic neurovascular bundle sacrifice is often required, and anterior spinal artery (ASA) perfusion can be compromised. Spinal angiography allows localization of variable ASA vascular contribution. This study's objective […]

Low back pain, often resulting from degenerative disc disease, affects up to 80% of the population at some point in their lives. The impact of preoperative radicular pain duration on discectomy outcomes remains inconclusive. We aim to compare the outcomes of lumbar discectomy for patients with […]

To report the long-term follow-up outcome of a 15-day-old neonate with congenital scoliosis treated with posterior-only hemivertebra bone-disc-bone osteotomy (BDBO) without internal fixation./r/nA 15-day-old neonate presented with a lumbar dorsal bulge exhibiting central ulceration and fluid […]

Suicides by power tools such as grinders are rare and present significant challenges in forensic investigation. Accurate differentiation between suicidal, homicidal, or accidental injuries is crucial, particularly when the circumstances surrounding the death are ambiguous. We report the case of a […]

BackgroundAdolescent idiopathic scoliosis represents a complex three-dimensional spinal deformity of unknown etiology. It frequently results in visible deformities, decreased daily functional capacity, impaired pulmonary function, and psychological distress. Personalized treatment options for […]

To evaluate the relationship between pain catastrophizing, treatment modality, pain intensity, and functional disability in patients with chronic lower back pain, while also accounting for the effects of kinesiophobia and self-efficacy using generalized linear mixed models. Secondary analysis of a […]

Osteoporosis is a common complication in patients with primary biliary cholangitis (PBC). This study aimed to compare the efficacy and safety of denosumab and zoledronic acid (ZOL) in treating osteoporosis in PBC patients./r/nThis multicenter, randomized, open-label trial enrolled Japanese patients […]

This case describes a woman in her 30s presenting with a 2 month history of thoracic pain, initially suspected to be costochondritis. The pain was unresponsive to conservative management, and imaging revealed a paravertebral mass at the T6-T7 level. The differential diagnosis included malignancy, […]

: Congenital scoliosis (CS) is a developmental disorder characterized by abnormal vertebral development during embryogenesis. Despite the identification of genes involved in vertebral development, the underlying genetic causes of CS remain largely unknown. Monozygotic (MZ) twins discordant for CS […]

Synthesised data on the global prevalence of scoliosis in children and adolescents and its associated risk factors remain scarce. This systematic review aimed to estimate the global prevalence of scoliosis in children and adolescents and identify associated risk factors in children and […]

The optimal surgical approach for managing multilevel cervical disc degeneration remains debatable, particularly regarding the comparative efficacy and safety of hybrid surgery (HS) versus anterior cervical discectomy and fusion (ACDF). This meta-analysis aimed to evaluate the efficacy and safety […]

Obesity and the development of osteoporosis are closely related to abnormal visceral fat metabolism. The METS-VF is a novel body fat measurement method that integrates gender, waist circumference, and insulin resistance index. The purpose of this study was to look into the connection between […]

For decades, researchers have worked to unravel the mysteries of post-traumatic epilepsy (PTE), a form of epilepsy that emerges after a traumatic brain injury (TBI). Now, a new study led by Texas A&M University neuroscientist Dr. Samba Reddy offers a sweeping view of how far the science has […]

AO Spine NA Webinar— Managing Complications

A research collaboration involving scientists and students at The University of Texas at Dallas has found a clear connection between chronic sickle cell disease pain and the bacteria present in the gastrointestinal tract.

As a minimally invasive technique, Fu's subcutaneous needling (FSN) has been widely adopted in Chinese clinical practice for managing neck-type cervical spondylosis (CS). However, current evidence regarding its therapeutic efficacy remains inconclusive due to methodological limitations in existing […]

AO Spine NA Webinar—Pediatric Deformity

January 2023 In this month's update you will find the new export functionality that allows you to safely export your clinical cases directly from CaseFolio to your device. The post New in January: case export appeared first on myAO.

December 2022 You can now choose what you want to see on your myAO feed! In this month's update you will find a new feed design and experience divided into network activity and knowledge updates. The post New in December – A new feed experience appeared first on myAO.

Call for applications: AO Spine Education Commission Chairperson

Open call: AO Spine 2021 Research Start-up Grant