With the increasing aging population, the number of patients undergoing lumbar spinal surgery for degenerative changes is rising. In the United States, spinal fusion surgery ranked sixth in operating room procedures, accounting for 3.2% of all such procedures, with an aggregate cost for stays […]

Assess the effectiveness of traditional Chinese exercises in treating postmenopausal osteoporosis (PMOP) for evidence-based treatment support./r/nDesign by March 2024, we conducted a thorough search across 8 databases for eligible randomized controlled trials (RCTs). Meta-analysis was conducted […]

L4-5 lumbar degenerative spondylolisthesis is a common spinal disease in the middle-aged and elderly population, often accompanied by spinal stenosis and nerve root compression, which seriously affects the quality of life. Traditional posterior lumbar interbody fusion (PLIF) has been widely used in […]

Ofatumumab is a fully human anti-CD20 monoclonal antibody that selectively and highly depletes B cells. However, limited data on ofatumumab treatment are available in patients with neuromyelitis optica spectrum disorders (NMOSD). In this study, we aimed to evaluate the efficacy and safety of […]

Multiple sclerosis (MS) and ankylosing spondylitis (AS) rarely coexist. Due to possibly progressive course of disease, both AS and MS may require biological treatment. Tumor necrosis alpha (TNF-alpha) inhibitors are a group of biologics approved for treatment of AS (e.g. adalimumab, certolizumab […]

Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) is a rare neurodegenerative disorder due to mutations in the SACS gene. While the typical phenotype is characterized by cerebellar ataxia, spasticity, and peripheral neuropathy, more reports are published of atypical and […]

Circinate balanitis is a characteristic mucocutaneous lesion commonly associated with reactive arthritis (ReA), previously described as Reiter's disease. It typically presents alongside other ReA symptoms, including urethritis, conjunctivitis, and arthritis, but can occasionally occur as an […]

Spinal Dural Arteriovenous Fistulas (DAVFs) are rare vascular malformations characterized by abnormal connections betweena spinal artery and venous plexus. Though uncommon, DAVFs can be misdiagnosed due to their presentation with nonspecific symptoms, leading to potential treatment delays or […]

Surgical fixation for occipitocervical instability can be challenging due to limitations in occipital instrumentation that include prominent hardware, limited fixation points on the occiput, and the risk of intracranial injury. Occipital instrumentation is particularly difficult in pediatric […]

Idiopathic scoliosis is a three-dimensional spinal deformity that typically develops during childhood or adolescence but may affect individuals across the lifespan. Regular monitoring is often necessary to detect progression and assess treatment effectiveness. Radiography remains the clinical gold […]

BACKGROUNDInter- and intraindividual fluctuations in pain intensity pose a major challenge to treatment efficacy, with a majority of people perceiving their pain relief as inadequate. Recent preclinical studies have identified circadian rhythmicity as a potential contributor to these fluctuations […]

Chronic low back pain (cLBP) is common. Physiotherapy is frequently indicated as a non-pharmacological management of these patients. This Bayesian network meta-analysis compared active versus passive physiotherapy versus their combination in terms of pain and disability in patients with mechanical […]

Robot-assisted surgery (RAS) is increasingly used among younger patients. However, current literature often focuses on pairwise comparisons, which limits a comprehensive evaluation of robotic effectiveness across diverse conditions. This single-arm meta-analysis aimed to evaluate the effectiveness […]

We report a novel presentation of autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) in a 9-year-old Moroccan male patient born to consanguineous parents, expanding the known clinical spectrum of the disease. The patient presented to a tertiary care hospital in Rabat, Morocco, in […]

Motorcycle crash fatalities remain a significant public health concern. Traumatic brain injury is a leading cause of death following motorcycle crash. We aim to provide evidence-based guidelines pertaining to helmet use and helmet laws with respect to important outcomes including mortality, […]

Severe rigid adolescent idiopathic scoliosis (AIS) with Cobb angles ≥100° presents surgical challenges due to its structural stiffness and high complication rates. The optimal surgical approach remains debated, particularly between single-stage and multiple-staged correction. The aim of this […]

Degenerative spinal diseases may lead to multisegmental instabilities and present as de novo scoliosis. Due to frequent primary and secondary complications, their treatment is controversial among spine surgeons. The aim of this systematic review is to investigate the postoperative quality of life […]

Chordoid meningioma (CM) is an uncommon histological variant of meningioma, typically found intracranially. Intraspinal occurrences, particularly in the cervical region, are exceedingly rare. We report a unique case of a 73-year-old male with cervical spinal CM who experienced tumor recurrence two […]

AO Spine NA Webinar— Managing Complications

The occurrence of a vertebral fracture in a pregnant woman presents unique challenges in terms of diagnosis and therapeutic. Managing such cases requires multidisciplinary collaboration to minimize x-rays and preserve fetus development while ensuring efficient treatment of the fracture in the […]

Lumbar nerve root schwannomas are rare tumors that can cause debilitating radicular pain and motor dysfunction due to nerve root compression. This study introduces a novel minimally invasive transpars approach for their removal, aiming to preserve spinal stability while ensuring complete […]

Thymic tumors are rare in the general population, and to the best of our knowledge, no cases of thymoma have been described in patients with rheumatic diseases treated with tumor necrosis factor (TNF)-α inhibitors, except for the case of a patient receiving infliximab for Crohn's disease (CD) who […]

Ion homeostasis is disrupted following nerve injury, and elevated Ca levels have been reported to induce Schwann cell (SC) death. Notably, clinical interventions such as electrical stimulation enhance Ca influx and facilitate nerve regeneration. These findings highlight the need to clarify the […]

Tumor Talks - Simon Lo, MD, Serah Choi MD, PhD, Tony Wang, MD

A research collaboration involving scientists and students at The University of Texas at Dallas has found a clear connection between chronic sickle cell disease pain and the bacteria present in the gastrointestinal tract.

When we think of movement disorders, the tremors associated with Parkinson's disease are probably what first spring to mind. However, there are other equally debilitating and much less well-known conditions that profoundly affect quality of life for those who suffer from them.

To assess the effectiveness of a checklist for disease activity and comorbidity control in patients with axial spondyloarthritis (axSpA)./r/nA quasi-experimental retrospective multicentre pre-post intervention study was carried out in Spain between 2016 and 2022. Improvement in disease activity and […]

Positional asphyxia refers to asphyxia resulting from an abnormal body posture that obstructs pulmonary ventilation. We report two cases in which individuals were unable to escape from positions that interfered with respiration, and cervical fractures were found upon autopsy. In the first case, a […]

As a minimally invasive technique, Fu's subcutaneous needling (FSN) has been widely adopted in Chinese clinical practice for managing neck-type cervical spondylosis (CS). However, current evidence regarding its therapeutic efficacy remains inconclusive due to methodological limitations in existing […]

Transforaminal Approaches – Which One to Choose John Ogunlade, D.O.

In this case report we present a rare cause of central sleep apnea secondary to severe cervical stenosis in a young male after excluding all the possible causes of central sleep apnea./r/nRashed AN, Bedaiwi N. Spinal stenosis as a rare cause of central sleep apnea: a case report. . […]

Pulmonary cement embolism (PCE) is a rare but severe complication following percutaneous vertebroplasty (PVP). Calcium phosphate cement (CPC) has emerged as an alternative to traditional materials for vertebral augmentation. There appear to be no established guidelines for managing symptomatic PCE, […]

The prevalence of osteoporosis, particularly among the elderly population and postmenopausal women (PMW), remains a significant public health concern. Women aged 50 to 60 years are especially vulnerable to osteoporosis-related bone loss, emphasizing the need for preventative measures and early […]

AO Spine NA Webinar—Pediatric Deformity

January 2023 In this month's update you will find the new export functionality that allows you to safely export your clinical cases directly from CaseFolio to your device. The post New in January: case export appeared first on myAO.

December 2022 You can now choose what you want to see on your myAO feed! In this month's update you will find a new feed design and experience divided into network activity and knowledge updates. The post New in December – A new feed experience appeared first on myAO.

Call for applications: AO Spine Education Commission Chairperson

Open call: AO Spine 2021 Research Start-up Grant