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  • Mechanisms and management of self-resolving lumbar disc herniation: bridging molecular pathways to non-surgical clinical success.
    on June 3, 2025

    Spontaneous resorption of lumbar disk herniation (LDH) presents a promising avenue for the non-surgical management of herniated disks. Here we present a 40-year-old female with severe L5/S1 herniation who experienced spontaneous resorption confirmed by MRI. The patient adhered to a comprehensive […]

  • Primary neurolymphomatosis presenting as paraparesis and diplopia in a young man.
    on June 3, 2025

    A man in his mid-20s presented with a 5-month history of bilateral lower limb weakness and wasting along with bladder symptoms and erectile dysfunction. Additionally, he had binocular diplopia and progressive drooping of both eyelids. His clinical presentation was suggestive of bilateral third […]

  • Identifying predictors of brace treatment outcomes for adolescents or adults with idiopathic scoliosis: a systematic review.
    on June 3, 2025

    This systematic review aimed to identify predictors of brace treatment outcomes for adolescents or adults with idiopathic scoliosis./r/nFour databases including MEDLINE, EMBASE, Web of Science, and CINAHL were searched. Free text and indexed terms identifying the populations, predictions analyses […]

  • Pulmonary function does not improve after 10 years of posterior spinal fusion in adolescent idiopathic scoliosis: a systematic review and meta-analysis.
    on June 3, 2025

    This systematic review and meta-analysis aimed to comprehensively assess the medium- and long-term effects of PSF on respiratory function in patients with adolescent idiopathic scoliosis (AIS) through a systematic review and meta-analysis./r/nFour major databases were searched. Mean differences and […]

  • Impact of surgical treatment for adolescent idiopathic scoliosis on maternal and obstetric outcomes: a meta-analysis.
    on June 3, 2025

    To compare the maternal and obstetric health outcomes between pregnant AIS patients treated surgically (AIS surgery), pregnant AIS patients treated conservatively (AIS conservative), and pregnant healthy controls./r/nA systematic review and meta-analysis were conducted according to the PRISMA […]

  • Salvage therapy of complicated Candida albicans spondylodiscitis with Rezafungin.
    on June 3, 2025

    Invasive fungal infections, particularly those caused by Candida species, represent an increasing cause of hospital-related morbidity and mortality. Most commonly Candida spp. is the causative agent of candidemia and invasive candidiasis. In this report we present a complex case of Candida albicans […]

  • Expanding the Genetic Framework: Insights into Non-HLA-B27 Contributions to Axial Spondylarthritis.
    on June 3, 2025

    Spondylarthritis is a complex group of inflammatory diseases closely associated with the HLA-B27 antigen. However, the role of non-HLA-B27 alleles in the disease's pathogenesis has gained significant scholarly attention in recent years. : This case study presents a 49-year-old male with a history […]

  • Staged Versus Simultaneous Surgery for Adult Spinal Deformity : A Systematic Review and Meta-analysis.
    on June 3, 2025

    Systematic review and meta-analysis./r/nTo assess the safety and efficacy of staged versus same-day spinal fusion surgeries in adult spinal deformity (ASD)./r/nASD surgeries are associated with high complication rates, ranging from 10% to 40%. Among the strategies to enhance safety, staging the […]

  • Association of Polymorphisms (, , and ) with Susceptibility to Lumbar Disc Herniation: Systematic Review, Meta-Analysis, Trial Sequential Analysis, and Transcriptional Prediction.
    on June 3, 2025

    : Lumbar disc herniation (LDH) is influenced by genetic, mechanical, and behavioral factors, with genetic predisposition playing a key role. () polymorphisms have been implicated in LDH susceptibility, warranting further investigation. This study aimed to assess the association between […]

  • Anterior Cervical Discectomy and Fusion vs. Anterior Cervical Corpectomy and Fusion for 2-Level Degenerative Cervical Myelopathy: A Systematic Review and Meta-Analysis.
    on June 3, 2025

    Cervical spondylotic myelopathy (CSM) is a common cause of progressive neurological decline in elderly patients, often necessitating surgical decompression. Anterior cervical discectomy and fusion (ACDF) and anterior cervical corpectomy and fusion (ACCF) are commonly used procedures. However, there […]

  • Optimal resistance training parameters for improving bone mineral density in postmenopausal women: a systematic review and meta-analysis.
    on June 3, 2025

    This meta-analysis aims to explore the effects of resistance training on bone mineral density (BMD) in postmenopausal women, specifically focusing on different training intensities, durations, frequencies, and periods, across various skeletal sites lumbar spine (LS), femoral neck (FN), total hip […]

  • Historical evolution, management, and outcome of surgical treatment for high-grade spondylolisthesis: a systematic review.
    on June 3, 2025

    High-grade spondylolisthesis (HGSL) is a rare condition characterized by a vertebral slippage of more than 50% relative to the inferior adjacent vertebra. Despite the range of surgical techniques available, there is no consensus regarding the optimal management approach for HGSL. Although various […]

  • Comparison of outcomes between cervical disc arthroplasty and anterior cervical discectomy and fusion for the treatment of cervical spondylotic myelopathy: a systematic review and meta-analysis.
    on June 3, 2025

    The management of cervical spondylotic myelopathy (CSM) presents a clinical conundrum, with cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF) emerging as primary contenders. However, the comparative advantages and limitations of these interventions remain […]

  • Sacroiliac damage on MRI in axial spondyloarthritis and chronic back pain, women with postpartum back pain, runners and healthy subjects.
    on June 3, 2025

    To investigate the extent and performance of structural lesions in sacroiliac joints on MRI (MRI-SI) in patients with axial spondyloarthritis (axSpA), chronic back pain, postpartum back pain, runners and healthy subjects./r/nMRI-SIs in 172 subjects, including 47 patients with diagnosed axSpA […]

  • AO Spine NA Webinar—Pediatric Deformity
    on May 30, 2025

    AO Spine NA Webinar—Pediatric Deformity

  • Tinnitus - Imaging and Management - Timo Krings, MD, PhD, MSc
    on May 29, 2025

    Tinnitus - Imaging and Management - Timo Krings, MD, PhD, MSc

  • Difficult Lateral Cases - Rod J Oskouian, Jr, M.D.
    on May 27, 2025

    Difficult Lateral Cases - Rod J Oskouian, Jr, M.D.

  • A Novel Homozygous Frameshift Variant of SACS Gene in the Turkish Siblings With Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS).
    on May 26, 2025

    Pathogenic variants of sacsin (SACS) gene cause autosomal recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS). It is a hereditary neurological disorder manifested with gait ataxia, intentional tremor, lower limb pyramidal signs and pes cavus. It was originally described in the late 1970s and […]

  • Minimally invasive laparoscopic and robotic anterior lumbar interbody fusion: a systematic review and future directions.
    on May 26, 2025

    Anterior Lumbar Interbody Fusion (ALIF) is a commonly performed spine surgery procedure used to treat lumbar conditions such as degenerative disc disease, spondylolisthesis, and spinal deformities. Traditionally, it has been performed using open and mini-open surgical techniques. Recently, however, […]

  • Body perception outcome measures in chronic non-specific low back pain: A systematic review of measurement properties using the COSMIN approach.
    on May 26, 2025

    Chronic low back pain (CLBP) is a highly prevalent health problem. Recent research has suggested that disruption of body perception might contribute to the problem and represent a target for treatment. Valid and reliable outcome measures are required to understand the relationship between disrupted […]

  • Drop metastasis from the extradural to the intradural space in spinal Ewing's sarcoma - a novel case report.
    on May 26, 2025

    Spinal Ewing's Sarcoma is a rare tumour predominantly affecting children and adolescents. We describe the case of an 18-year-old male patient who first presented with a primary extradural cervical Ewing's sarcoma tumour, and 5 years later had a recurrence with thoracolumbar and lumbosacral […]

  • AO Spine NA Webinar—Clinical Biomechanics in Spinal Surgery
    on May 21, 2025

    AO Spine NA Webinar—Clinical Biomechanics in Spinal Surgery

  • Effectiveness and safety of thoracic segmental spinal anesthesia for breast surgery: A systematic review and meta-analysis.
    on May 19, 2025

    General anesthesia is the standard approach for thoracic and abdominal procedures; however, it has notable limitations, particularly in high-risk patients. Regional anesthesia techniques, such as thoracic segmental spinal anesthesia, have gained popularity due to their potential to reduce these […]

  • Effectiveness of virtual reality rehabilitation for cervical spinal cord injury: A systematic review and meta-analysis.
    on May 19, 2025

    This systematic review and meta-analysis evaluated the effectiveness of virtual reality (VR) rehabilitation in improving functional performance for patients with cervical spinal cord injury (CSCI), which affects both upper and lower limb function. Following the Preferred Reporting Items for […]

  • A meta-analysis of the incidence of intra-abdominal injuries associated with thoracic or lumbar flexion-distraction injuries.
    on May 19, 2025

    Intra-abdominal injuries (IAIs) are often associated with thoracic or lumbar flexion distraction injuries (TLFDIs) or Chance fractures. The incidence ranges from 10 to 50 % in previous literature./r/nTo synthesize data about the incidence of IAIs associated with TLFDIs./r/nWe searched PubMed, WOS, […]

  • Clinical manifestations, imaging characteristics, and surgical outcome of cervical spinal osteochondroma in pediatrics patients: a case base systematic review of an unusual tumor.
    on May 19, 2025

    Pediatric spinal osteochondroma is a rare, benign tumor that can be challenging to diagnose and treat, particularly in the cervical spine. This study aimed to explore the imaging characteristics, clinical manifestations, and surgical techniques used for these tumors in pediatric patients by […]

  • The gender difference in the effects of air pollution on the risk of spinal osteoarthritis in Chinese middle-aged and older adults: a prospective cohort study in China.
    on May 19, 2025

    This study aimed to investigate whether exposure to multiple ambient air pollutants (PM, PM, PM, O₃, and NO₂) elevates the risk of spinal osteoarthritis among middle-aged and older adults in China, and to further determine if there are gender-specific differences in vulnerability./r/nA total of […]

  • Imaging Considerations for Patients With Chronic Low Back Pain: A Case Report.
    on May 13, 2025

    The incidence of low back pain, a leading cause of global disability, has increased significantly. Spinal cord stimulation (SCS) is US Food and Drug Administration-approved for treating intractable back pain, particularly in patients with prior surgical interventions./r/nA 43-year-old woman was […]

  • Association between thoracolumbar fascia injury and residual back pain following percutaneous vertebral augmentation: a systematic review and meta-analysis.
    on May 13, 2025

    To evaluate the association between a thoracolumbar fascia injury (TLFI) and the development of residual back pain (RBP) following percutaneous vertebral augmentation (PVA)./r/nOsteoporotic vertebral compression fractures (OVCF) commonly affect elderly individuals and those with osteoporosis, […]

  • Clinical applications of 3D printing in spine surgery: a systematic review.
    on May 6, 2025

    The objective of this systematic review is to present a comprehensive summary of existing research on the use of 3D printing in spinal surgery./r/nThe researchers conducted a thorough search of four digital databases (PubMed, Web of Science, Scopus, and Embase) to identify relevant studies […]

  • Genetic analysis of three patients from two unrelated Chinese families with autosomal recessive spastic ataxia of Charlevoix-Saguenay.
    on May 6, 2025

    Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a rare early-onset neurodegenerative disorder characterized by progressive cerebellar ataxia, spasticity, and sensorimotor peripheral neuropathy. This disorder is caused by homozygous or compound heterozygous variants in the […]

  • A Deep Learning Model for Three-Dimensional Determination of Whole Thoracic Vertebral Bone Mineral Density from Noncontrast Chest CT: The Multi-Ethnic Study of Atherosclerosis.
    on March 17, 2025

    Background Recent studies have investigated how deep learning (DL) algorithms applied to CT using two-dimensional (2D) segmentation (sagittal or axial planes) can calculate bone mineral density (BMD) and predict osteoporosis-related outcomes. Purpose To determine whether TotalSegmentator, an […]

  • Scientists discover 'entirely unanticipated' role of protein netrin1 in spinal cord development
    on November 14, 2024

    Researchers have uncovered a surprising new role for netrin1, a crucial protein in neural development, as a regulator that limits bone morphogenetic protein signaling in the developing spinal cord.

  • Research reveals link between spinal muscular atrophy and liver damage
    on July 17, 2024

    An international study has discovered that people living with the neurodegenerative condition spinal muscular atrophy (SMA) are at higher risk of developing fatty liver disease, suggesting that SMA patients may face additional health problems over time. This finding raises significant concerns […]

  • New in January: case export
    on January 26, 2023

    January 2023 In this month's update you will find the new export functionality that allows you to safely export your clinical cases directly from CaseFolio to your device. The post New in January: case export appeared first on myAO.

  • New in December – A new feed experience
    on December 2, 2022

    December 2022 You can now choose what you want to see on your myAO feed! In this month's update you will find a new feed design and experience divided into network activity and knowledge updates. The post New in December – A new feed experience appeared first on myAO.

  • Call for applications: AO Spine Education Commission Chairperson
    on February 24, 2022

    Call for applications: AO Spine Education Commission Chairperson

  • Open call: AO Spine 2021 Research Start-up Grant
    on February 21, 2022

    Open call: AO Spine 2021 Research Start-up Grant

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