The glymphatic system maintains brain homeostasis through cerebrospinal fluid transport and waste clearance. Its potential involvement in chemotherapy-related cognitive impairment remains largely unexplored due to limited in vivo evidence. In this prospective longitudinal study, 126 female breast […]

Spinocerebellar ataxia type 8 (SCA8) is a rare neurodegenerative disease that is caused by CAG/CTG repeat expansion in the overlapping ATXN8 and ATXN8OS genes and basically entails slowly progressive cerebellar dysfunction with resultant dysarthria, limb incoordination, and gait instability. […]

To describe the technique of closing-opening vertebral column resection (COVCR) in an adult patient with severe thoracolumbar kyphosis secondary to two adjacent posterior hemivertebrae./r/nCOVCR is a rare technique as it can only be applied in a very specific deformity configuration./r/nWe report […]

Astroblastomas (ABs) are rare glial tumors categorized by MN1 gene alterations in the WHO 2021 CNS tumor guidelines. While previously reported primarily in cerebral hemispheres, there have been few reports regarding primary spinal ABs, and no established guidelines have been published on the […]

Pelvic incidence (PI) is traditionally considered a constant anatomic parameter in adult spinal deformity (ASD) surgery. However, emerging evidence suggests that PI may change postoperatively, potentially influencing sagittal balance and mechanical complications. This study aims to systematically […]

The presented study aimed to identify risk factors for spinal deformity (SD) following resection of intradural spinal cord tumors via posterior approach./r/nArticles of interest were found in accordance with PRISMA guidelines utilizing the following databases: PubMed, Web of Science, and Scopus. […]

Degenerative lumbar diseases (DLDs) often have significant impacts on patients' quality of life, particularly when cage retropulsion (CR) occurs following lumbar interbody fusion (LIF). In this study, we conducted a meta-analysis to assess the risk factors associated with CR after LIF./r/nWe […]

Occult cerebrospinal fluid (CSF) leakage after lumbar spine surgery is common; however, cases in which CSF leakage leads to cauda equina tethering are rare and may result in severe neurological symptoms. This study elucidates the diagnostic challenges and management strategies for this rare […]

'Can't Intubate Can't Oxygenate' (CICO) situation is a life-threatening emergency, and an uncommon event in the healthy paediatric population. In children without anatomical airway anomalies, this scenario is most often due to laryngospasm or airway obstruction and can in most cases, be reversed […]

In this case report we present a rare cause of central sleep apnea secondary to severe cervical stenosis in a young male after excluding all the possible causes of central sleep apnea./r/nRashed AN, Bedaiwi N. Spinal stenosis as a rare cause of central sleep apnea: a case report. . […]

Chronic low back pain (cLBP) is extremely common and is one of the Chronic Overlapping Pain Conditions (COPCs), 10 conditions thought to have similar underlying pathophysiology. Little is known about the prevalence and co-occurrence of cLBP with other commonly accepted conditions referred to as […]

The Chinese Society for Therapeutic Radiology Oncology, the Chinese Anti-Cancer Association, the Chinese Society of Clinical Oncology, the Head and Neck Cancer International Group, the European Society for Radiotherapy and Oncology, and the American Society for Radiation Oncology collaboratively […]

A 12-year-old girl with neurofibromatosis type 1 presented with progressive thoracic scoliosis and neurological deficit. Imaging revealed a dystrophic curve, dorsal syrinx, and tethering of the cord by a plexiform neurofibroma arising from the T7 dorsal ramus. She underwent staged surgery: […]

We present the case of a 54-year-old patient treated with cemiplimab, an immune checkpoint inhibitor (ICI), for multiple basal cell carcinomas in the context of Gorlin Goltz syndrome. Gorlin Goltz syndrome is an autosomal dominant multisystem disorder characterized, among other features, by […]

Sacroiliac joint (SIJ) pain is a prevalent cause of chronic low back pain (LBP), affecting many adults in the United States. The SIJ provides stability and proper weight distribution from the trunk. Degenerative disruption to this joint can result in shearing and tension that can lead to […]

Prone PPT vs LLIF vs OLIF Evolution - Luiz Pimenta, M D

Contractures, pterygia, and spondylocarpotarsal fusion syndrome (CPSFS) comprises a group of extremely rare genetic disorders characterized by congenital craniofacial and musculoskeletal abnormalities. With fewer than 500 cases reported globally, this scarcity contributes to limited clinical […]

The microbial world encompasses a vast array of organisms, many of which remain poorly understood, yet possess the capacity to cause significant disease in humans. Roseomonas species, originally described in 1993 by Rihs et al., are amongst the less frequently encountered bacteria that can be […]

Area postrema syndrome is one of the core clinical features of neuromyelitis optica spectrum disorders (NMOSD), characterized by intractable hiccups, nausea, and vomiting. Brain MRI often reveals lesions in the dorsal medulla oblongata. However, recurrent syncope has rarely been described in NMOSD. […]

A catheterisable continent channel (CCC) is indicated in the treatment of neurogenic bladder. The most performed CCC is the Mitrofanoff's appendicovesicostomy. In case of unavailable cecal appendix, a Monti's ileovesicostomy, consisting in a tubularised ileal conduit, could be performed. This […]

Our aim was to evaluate long-term effectiveness and safety of cervical disc arthroplasty (CDA) compared to anterior cervical discectomy and fusion (ACDF) in single-segment cervical degenerative disc disease (CDDD)./r/nComprehensive literature searches were performed in four databases from their […]

Pulmonary cement embolism (PCE) is a rare but severe complication following percutaneous vertebroplasty (PVP). Calcium phosphate cement (CPC) has emerged as an alternative to traditional materials for vertebral augmentation. There appear to be no established guidelines for managing symptomatic PCE, […]

Axial spondyloarthritis (axSpA) and diffuse idiopathic skeletal hyperostosis (DISH) exhibit substantial overlap in clinical symptoms and imaging features, frequently resulting in diagnostic errors. This case study delves into a patient initially misdiagnosed with axSpA but later confirmed to have […]

BackgroundThe golden time for treatment of adolescent idiopathic scoliosis (AIS) is short, and how to effectively improve treatment outcomes to avoid surgery has been a focus of medical attention. Scoliosis orthoses are the preferred method of conservative treatment for AIS, but there are […]

Developing your Endo Practice: The Good, the Bad, and the Ugly - Choll Kim, MD

Vertebral dissections are a recognized cause of stroke in young people. Its association with Klippel-Feil Syndrome (KFS) is unusual. We describe the case of a male with simultaneous bilateral vertebral artery dissection with SKF and review the related literature. A 30-year-old male, with no […]

A 25-year-old severely obese woman sustained a knee injury with foot drop after an electric scooter crash. Initially diagnosed with a knee sprain and advised to follow-up with her primary care physician, she was later diagnosed with chronic multiligamentous knee instability and complete common […]

Camptocormia is a debilitating postural abnormality associated with Parkinson disease (PD), significantly impairing the daily lives of affected patients. Treatment options remain inconsistent, with lidocaine injections emerging as a potential therapy. However, the lack of standardized protocols […]

The prevalence of osteoporosis, particularly among the elderly population and postmenopausal women (PMW), remains a significant public health concern. Women aged 50 to 60 years are especially vulnerable to osteoporosis-related bone loss, emphasizing the need for preventative measures and early […]

This multicentre, retrospective case series analysed bone mineral density (BMD) changes in 26 patients who switched early from romosozumab (3-10 months) to antiresorptives. BMD gains over 12 months were similar to those in patients (n = 99) completing the full 12-month course./r/nRomosozumab […]

AO Spine NA Webinar—Pediatric Deformity

AO Spine NA Webinar—Clinical Biomechanics in Spinal Surgery

Researchers have uncovered a surprising new role for netrin1, a crucial protein in neural development, as a regulator that limits bone morphogenetic protein signaling in the developing spinal cord.

An international study has discovered that people living with the neurodegenerative condition spinal muscular atrophy (SMA) are at higher risk of developing fatty liver disease, suggesting that SMA patients may face additional health problems over time. This finding raises significant concerns […]

January 2023 In this month's update you will find the new export functionality that allows you to safely export your clinical cases directly from CaseFolio to your device. The post New in January: case export appeared first on myAO.

December 2022 You can now choose what you want to see on your myAO feed! In this month's update you will find a new feed design and experience divided into network activity and knowledge updates. The post New in December – A new feed experience appeared first on myAO.

Call for applications: AO Spine Education Commission Chairperson

Open call: AO Spine 2021 Research Start-up Grant