The human 16p11.2 BP4-BP5 region, composed of low-copy repeats, is prone to mediating recurrent copy number variations that increase the risk of neurodevelopmental disorders. Compared with 16p11.2 deletion variants, duplication variants have lower penetrance and higher phenotypic heterogeneity. Due […]

Ovarian fibromas, especially those of the mitotically active cellular subtype, are very rare in children; however, children with nevoid basal cell carcinoma syndrome (NBCCS) are prone to these neoplasms. We present a 12-year-old girl with an ovarian mitotically active cellular fibroma (MACF) with […]

Significant advances have been made in detecting RNA markers that may indicate malignancy in fine needle aspiration cytology (FNAC) samples./r/nTo review the roles of protein-coding and non-coding RNAs in differentiating between malignant and benign thyroid nodules./r/nA comprehensive literature […]

Endoscopic and surgical treatment are the two most common treatment strategies for resectable esophageal cancer (EC), but the optimal treatment for T1b EC remains controversial. This study aims to compare the efficacy and safety of endoscopic treatment versus esophagectomy for T1b EC./r/nWeb of […]

Distraction osteogenesis has been the preferred treatment modality for patients with hemifacial microsomia. Although an immediate improvement in facial asymmetry is noted at the completion of the procedure, long-term data regarding postdistraction stability is rare. In this study, a ≥12-year […]

A male patient presented to the Otolaryngology Emergency Department with progressive onset of left facial, cervical and submandibular swelling and history of bleeding from the oral cavity, 5 hours following extraction of teeth 28 and 38. On physical examination, the patient had a violet-coloured, […]

Patulous Eustachian tube (PET) refers to condition where the Eustachian tube remains abnormally open or fails to close adequately, leading to autophony, aural fullness, breathing autophony, tinnitus, and hypernasality. This case study reports the acoustic characteristics of a PET patient with […]

The Cardiometabolic Index (CMI) is a new indicator of visceral fat distribution and dysfunction that can be calculated using lipid parameters, waist circumference, and height. The relationship between CMI and Obstructive Sleep Apnea (OSA) remains unclear. This cross-sectional study explored the […]

The differences in outcomes between dorsal preservation (DP) and dorsal reduction (DR) techniques in rhinoplasty remain unclear. This meta-analysis evaluates the DP and DR in terms of functional and aesthetic outcomes, revisions surgeries, dorsal irregularities, and residual and recurrent […]

This research aimed to assess the efficacy of ibuprofen and low-level laser therapy (LLLT) in pain reduction following the placement of elastomeric separators, utilizing a network meta-analysis (NMA) to synthesize data from relevant randomized controlled trials (RCTs). Our objective was to […]

This umbrella review aims to determine if clear aligners promote cytotoxic and estrogenic effects./r/nThe review was conducted in conformity with the PRISMA statement. A systematic search was carried out in March of 2025 in 5 databases (Medline through PubMed, Web of Science (all databases), […]

Obstructive sleep apnea (OSA) is a highly prevalent sleep disorder. Misdiagnosis might lead to several systemic conditions, including hypertension, vascular damage, and cognitive impairment. The gold-standard diagnostic tool for OSA is polysomnography, which is expensive, time-consuming, and not […]

Orbital mucinous tumors are exceptionally rare, with multifocal systemic involvement posing significant diagnostic and therapeutic challenges. This study aims to characterize the radiological and pathological features of such cases, refine differential diagnosis criteria, and evaluate treatment […]

General anesthesia in patients with undiagnosed hypothyroidism can lead to neurological, pulmonary, and cardiovascular complications. We report a case of hypothyroidism in a patient with treatment-resistant depression detected intraoperatively based on multiple clinical findings. A 49-year-old […]

Autologous fat injection has been proposed as a potential alternative to traditional rhinoplasty. However, the technique has been criticized for its disappointing retention and the potential complications associated with underfilling./r/nTo summarize data on patient satisfaction, retention, […]

Glomangiopericytomas are rare spindle cell neoplasms that typically arise within the sinonasal tract and exhibit borderline to low malignant potential. While unusual, occurrences of this tumor in other regions of the head and neck have been reported, such as the deep neck spaces, larynx, tongue, […]

Loeys-Dietz syndrome is a rare connective tissue disorder characterized by the formation of aggressive arterial aneurysms. There are a few reports of Loeys-Dietz syndrome with pseudoaneurysms causing simultaneous pancreatic and biliary stenoses. Herein, we report the case of a 42-year-old man with […]

The aim of this research was to determine the soft-to-hard tissue ratio using three-dimensional (3D) analysis in different types of orthognathic surgery and to update the most recent scientific evidence provided in 2017. A systematic search covering the period January 2017-December 2023 was […]

The genetic roles of protein-encoding genes in nonsyndromic cleft lip with or without cleft palate (NSCL/P) susceptibility have been intensively studied, but many gaps remain including the emerging roles of long non-coding RNA. In this study, we found that NSCL/P risk-associated SNPs may have […]

To evaluate the frequency of tooth anomalies (TA) in the deciduous and permanent dentition of patients with nonsyndromic orofacial clefts (NSOC), both inside and outside the cleft area./r/nThe following databases were searched for the relevant literature: Cochrane, OVID, SciELO, Embase, Livivo, […]

Le Fort III surgical procedures are used for midface advancement in patients with syndromic craniosynostosis. Three-dimensional (3D) computed tomography (CT) offers significant advantages in planning and evaluating surgical outcomes. It aids in determining the appropriate surgical procedure and […]

The objective of this study was to assess the prevalence of different complications of temporomandibular joint replacement surgery in adult patients. An electronic search of PubMed, Embase, Web of Science Core Collection and Google Scholars was performed. Clinical studies with at least 10 patients […]

Mandibular reconstruction with a fibula free flap is often used for advanced oral malignancies, osteonecrosis, or benign tumors to restore function and appearance after segmental mandibulectomy. The "Jaw in a Day" (JIAD) technique enables immediate restoration of form and function with a fibula […]

Immunotherapies are undoubtedly transforming the landscape of cancer treatment worldwide. By harnessing the body's immune system to fight disease, they can achieve outcomes in advanced cancers that are impossible with conventional methods. However, these revolutionary therapies don't work equally […]

A decade ago, a clinical trial in the U.K. famously showed that children who were exposed to peanuts in the early months of life had reduced risk of developing a peanut allergy compared with children who avoided peanuts.

Relief from decade long pain after a life changing upper jaw surgery

Craniofacial Fibrous Dysplasia Surgery with Removal of Fibrous Bone

Augmentation rhinoplasty using alloplastic materials is a relatively standard procedure in Asian patients. Expanded polytetrafluoroethylene (ePTFE) is one of the commonly used alloplastic materials because it has a high biocompatibility and is easy to handle. Recently, a patient who had previously […]

External nasal deformity is common and can be treated surgically. It often occurs in conjunction with the development of the nasal septal cartilage, vomer, and vertical plate of the ethmoid bone but may be caused by trauma. Here, we present a case of external nasal deformity caused by trauma. A […]

Reconstructing late deformities of the orbitozygomaticomaxillary complex after inadequate treatment of facial fractures requires zygomatic osteotomy to reposition the bony fragments to their anatomical position. However, confirming the position of the bone fragments can be challenging due to the […]

AO CMF NA Course—Hot Topics in CMF Reconstruction (with human anatomical specimens) w/ Dr. Rodriguez

to investigate the ability of mandibular distraction osteogenesis (MDO) to avoid gastrostomy tube (G-tube)./r/nPubMed, EBSCOhost, Cochrane, and Embase./r/nWe retrospectively reviewed the number of MDO cases performed at our institution for patients with Robin Sequence (RS) over the past 10 years. […]

This case report describes the successful treatment of a patient with Crouzon syndrome with severe midfacial deficiency and malocclusion, including reverse overjet./r/nIn Phase I treatment, maxillary lateral expansion and protraction were performed. In Phase II treatment, after lateral expansion of […]

January 2023 In this month's update you will find the new export functionality that allows you to safely export your clinical cases directly from CaseFolio to your device. The post New in January: case export appeared first on myAO.

January 2023 The radial forearm free flap (RFFF) is a flap with ideal characteristics for lip reconstruction because it is thin and can be folded to restore both the skin and the inner lining. The post myAO CMF clinical case roundup on RFFF reconstruction of the Upper Lip appeared first on myAO.

Orbital Fornix Incision & Opthalmologic and Orbital Evaluation

A desire to help inspires star surgeon to share patient stories on YouTube